Investigating a persistent challenge
People using long-term indwelling urinary catheters often experience urinary tract infections, blockages and unscheduled catheter changes.
REDUCE is investigating whether NowCath Foley can reduce the rate of catheter changes compared with a conventional all-silicone Foley catheter.
Catheter changes
Scheduled and unscheduled
Blockage
Requiring catheter removal
CAUTI
Catheter-associated urinary tract infection
A different approach to urinary drainage
NowCath Foley is an all-silicone indwelling urinary catheter with two additional drainage eyelets positioned below the balloon. The design is intended to safely and effectively improve bladder emptying.
Designed to compare
REDUCE is a multicentre, prospective, randomised, blinded, controlled crossover clinical investigation. Each participant uses both catheters in a randomly assigned order.
Every participant. Both catheters.
Participants are randomly assigned to one of two study sequences.
NowCath Foley
Conventional Foley
Conventional Foley
NowCath Foley
Measuring catheter changes
The primary comparison is the incidence of catheter changes per 100 catheter days.
Catheter changes during the first 4-weeks of the study period.
Catheter changes during the full 12-weeks the study period.
Looking beyond catheter changes
The investigation also evaluates clinical outcomes, catheter condition, participant experience and care delivery.
Clinical outcomes
CAUTI, blockage requiring catheter removal, residual urine and time to asymptomatic bacteriuria.
Catheter condition
The presence and severity of catheter encrustation.
Participant experience
Catheter-related and general quality of life, comfort, satisfaction and catheter preference.
Care delivery
Ease of insertion, antibiotic use, safety, catheter-related complications and within-trial cost-effectiveness.
A multicentre investigation in Denmark
The REDUCE Trial is sponsored by Nowwell Flow Technology AS and conducted with clinical and municipal partners.
Frank Holden Mose, MD, PhD
Gødstrup Hospital, Department of Medicine
Currently recruiting in Denmark
Visit ClinicalTrials.gov for information about recruitment, eligibility, locations and study status.
No study results have been posted. NowCath Foley is being evaluated as an investigational device in the REDUCE Trial.
